DrugAge entry for Oxcarbazepine

Name: Oxcarbazepine
Synonyms: 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide • 10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide • 10-Oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide • 28721-07-5 • 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide • 5H-Dibenz(b,f)azepine-5-carboxamide, 10,11-dihydro-10-oxo- • 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-oxo- • 9-oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide • CHEBI:7824 • CHEMBL1068 • GP 47680 • GP-47680 • KIN-493 • MFCD00865307 • MLS000084586 • Oxacarbazepine • Oxcarbamazepine • Oxcarbazepina • OXCARBAZEPINE • Oxcarbazepinum • SMR000048684 • SPN-804 • Timox • Trileptal • UNII-VZI5B1W380 • VZI5B1W380
CAS Number: 28721-07-5
IUPAC Name: 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide
PubChem CID: 34312

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Oxcarbazepine

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Oxcarbazepine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Oxcarbazepine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id