DrugAge entry for Ononetin

Name: Ononetin
Synonyms: 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)-ethanone • 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethan-1-one • 1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone • 2',4'-dihydroxy-2-(4-methoxyphenyl)acetophenone • 2,4-dihydroxy-4'-methoxydeoxybenzoin • 487-49-0 • 4S084Z7YS4 • Acetophenone, 2',4'-dihydroxy-2-(p-methoxyphenyl)- • BSPBio_001797 • BSPBio_003273 • CHEMBL241858 • KBioGR_002057 • KBioSS_001276 • MFCD00020119 • MLS000736891 • NSC 89759 • NSC89759 • ONONETIN • Oprea1_716474 • Spectrum2_000808 • Spectrum3_001777 • Spectrum4_001479 • Spectrum5_000157 • Spectrum_000796 • SR-01000395029 • UNII-4S084Z7YS4
CAS Number: 487-49-0
IUPAC Name: 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone
PubChem CID: 259632

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Ononetin

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Ononetin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Ononetin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id