DrugAge entry for O6-benzylguanine

Name: O6-benzylguanine
Synonyms: 01KC87F8FE • 1000874-21-4 • 19916-73-5 • 1H-Purin-2-amine, 6-(phenylmethoxy)- • 2-Amino-6-(benzyloxy)purine • 2-Amino-6-(phenylmethoxy)-9H-purine • 2-amino-6-benzyloxypurine • 6-(benzyloxy)-1H-purin-2-amine • 6-(Benzyloxy)-7H-purin-2-amine • 6-(benzyloxy)-9H-purin-2-amine • 6-(Phenylmethoxy)-1H-purin-2-amine • 6-BENZYLGUANINE • 6-Benzyloxyguanine • 6-O-Benzylguanine • 6-phenylmethoxy-7H-purin-2-amine • 9H-Purin-2-amine, 6-(phenylmethoxy)- • CHEMBL407874 • KRX-0402 • MFCD00269931 • NSC-637037 • NSC637037 • O(6)-Benzylguanine • O(6)-Bgua • o6-benzylguanine • UNII-01KC87F8FE
CAS Number: 19916-73-5
IUPAC Name: 6-phenylmethoxy-7H-purin-2-amine
PubChem CID: 4578

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for O6-benzylguanine

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for O6-benzylguanine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for O6-benzylguanine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id