DrugAge entry for Nocodazole

Name: Nocodazole
Synonyms: 2-Benzimidazolecarbamic acid, 5-(2-thenoyl)-, methyl ester • 2-Benzimidazolecarbamic acid, 5-(2-thienylcarbonyl)-, methyl ester • 31430-18-9 • C14H11N3O3S • CHEMBL9514 • Methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate • methyl (5-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-yl)carbamate • Methyl 5-(2-thenoyl)-2-benzimidazolecarbamate • Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate • Methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate • Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate • MLS001164242 • N-(5-(2-Thenoyl)-2-benzimidazolyl)carbamic acid methyl ester • Nocodazol • nocodazole • Nocodazolum • NSC 238159 • NSC-238159 • NSC238159 • Oncodazole • R 17,934 • R 17934 • R-17934 • SH1WY3R615 • UNII-SH1WY3R615
CAS Number: 31430-18-9
IUPAC Name: methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
PubChem CID: 4122

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Nocodazole

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Nocodazole

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Nocodazole

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id