DrugAge entry for Nobiletin

Name: Nobiletin
Synonyms: 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one • 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one • 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one • 3',4',5,6,7,8-Hexamethoxyflavone • 478-01-3 • 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy- • 5,6,7,8,3',4'-Hexamethoxyflavone • CCRIS 9012 • CHEBI:7602 • CHEMBL76447 • D65ILJ7WLY • Flavone, 5,6,7,8,3',4'-hexamethoxy • Hexamethoxyflavone • MFCD03273560 • Nobiletin (Hexamethoxyflavone) • NSC 76751 • NSC-76751 • NSC76751 • SMR000156231 • UNII-D65ILJ7WLY
CAS Number: 478-01-3
IUPAC Name: 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one
PubChem CID: 72344

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Nobiletin

Average/Median Lifespan
Max Lifespan
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References

Yang, X et al. (2020) Nobiletin Delays Aging and Enhances Stress Resistance of Int J Mol Sci 21(1) PubMed

DGIdb Human Drug-Gene Interactions for Nobiletin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Nobiletin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id