DrugAge entry for Nicolsamide

Name: Nicolsamide
Synonyms: 2',5-Dichloro-4'-nitrosalicylanilide • 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide • 50-65-7 • Atenase • Bayluscid • Cestocid • Devermin • Devermine • Dichlosale • Fenasal • Helmiantin • Iomesan • Iomezan • Lintex • Mansonil • Nasemo • Niclocide • niclosamide • Phenasal • Radeverm • Sagimid • Sulqui • Tredemine • Vermitid • Yomesan
CAS Number: 50-65-7
IUPAC Name: 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
PubChem CID: 4477

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Nicolsamide

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Nicolsamide

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Nicolsamide

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id