DrugAge entry for Nebivolol

Name
Nebivolol 
Synonyms
(+)-Nebivolol • (-)-Nebivolol • 1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol • 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol] • 2H-1-Benzopyran-2-methanol, alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro- • 99200-09-6 • alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro)-2H-1-benzopyran-2-methanol • alpha,alpha'-(Iminodimethylene)bis(6-fluoro-2-chromanmethanol) • Bystolic • CHEBI:64019 • Lobivon • Nebicard-5 • Nebilet • Nebilong • Nebipill • Nebivolol • Nebivolol [USAN:INN:BAN] • Nebivololum • Nebivololum [Latin] • Nubeta • PI-21858 • R 67555 • R-67555 • R65,824 • Vasoxen 
CAS Number
99200-09-6 
IUPAC Name
1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol 
PubChem CID
71301 

Summary

Species No. Entries MAX(Avg/Med Lifespan Change %) MEAN(Avg/Med Lifespan Change %) MAX(Max Lifespan Change %) MEAN(Max Lifespan Change %)

Results

Compound/Formulation Species Sex Strain Dosage Avg/Med Lifespan Change (%) Avg/Med Lifespan Significance Max Lifespan Change (%) Reference

Lifespan Charts for Nebivolol


References

Spindler, SR et al. (2013) \u03b21-Adrenergic receptor blockade extends the life span of Drosophila and long-lived mice. Age (Dordr) 35(6)2099-2109 PubMed
Miller, RA et al. (2024) Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin. GeroScience 46(5)4657-4670 PubMed

DGIdb Human Drug-Gene Interactions for Nebivolol

Interaction Types Gene Symbol Common Name HGNC Id DGIdb Sources References

Stitch DB Human Drug-Protein Interactions for Nebivolol

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id