The Human Ageing Genomic Resources are at risk. Please support our work at JustGiving.

DrugAge entry for NSC 45923 (8-Methyoxypsoralen)

Name
NSC 45923 (8-Methyoxypsoralen) 
Synonyms
298-81-7 • 8-Methoxypsoralen • 8-Methoxypsoralene • 8-MOP • 9-Methoxy-7H-furo[3,2-g]chromen-7-one • Ammodin • Ammoidin • Meladinin • Meladinine • Meladoxen • Meloxine • Methoxa-Dome • methoxsalen • Oxsoralen • Oxsoralen-ultra • Oxypsoralen • Puvalen • Uvadex • XANTHOTOXIN • Xanthotoxine 
CAS Number
298-81-7 
IUPAC Name
9-methoxyfuro[3,2-g]chromen-7-one 
PubChem CID
4114 

Summary

Species No. Entries MAX(Avg/Med Lifespan Change %) MEAN(Avg/Med Lifespan Change %) MAX(Max Lifespan Change %) MEAN(Max Lifespan Change %)

Results

Compound/Formulation Species Sex Strain Dosage Avg/Med Lifespan Change (%) Avg/Med Lifespan Significance Max Lifespan Change (%) Reference

Lifespan Charts for NSC 45923 (8-Methyoxypsoralen)


References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for NSC 45923 (8-Methyoxypsoralen)

Interaction Types Gene Symbol Common Name HGNC Id DGIdb Sources References

Stitch DB Human Drug-Protein Interactions for NSC 45923 (8-Methyoxypsoralen)

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id