DrugAge entry for Myricetin

Name: Myricetin
Synonyms: 3,3',4',5,5',7-Hexahydroxyflavone • 3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-one • 3,5,7,3',4',5'-Hexahydroxyflavone • 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one • 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one • 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one • 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)- • 529-44-2 • AK111247 • BRN 0332331 • Cannabiscetin • CCRIS 5838 • CHEBI:18152 • CHEMBL164 • EINECS 208-463-2 • FLAVONE, 3,3',4',5,5',7-HEXAHYDROXY- • MFCD00006827 • MYC • myricetin • Myricetol • Myricitin • NSC 407290 • NSC-407290 • NSC407290 • Q-100601
CAS Number: 529-44-2
IUPAC Name: 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
PubChem CID: 5281672
SEP-L1000 side effects: Abdominal pain, Arthralgia, Asthenia, Diarrhoea, Dizziness, Headache, Hypersensitivity, Hypotension, Infection, Insomnia, Malaise, Nausea, Oedema, Pain, Paraesthesia, Pneumonia, Pruritus, Rash, Syncope, Thrombocytopenia, Urticaria, Vertigo, Vomiting

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Myricetin

Average/Median Lifespan
Max Lifespan
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References

Büchter, C et al. (2013) Myricetin-mediated lifespan extension in Caenorhabditis elegans is modulated by DAF-16. Int J Mol Sci 14(6)11895-11914 PubMed
Gregor Grünz (2012) Structural features and bioavailability of four flavonoids and their implications for lifespan-extending and antioxidant actions in C. elegans Mechanisms of Ageing and Development 133(1)1-10 PubMed

DGIdb Human Drug-Gene Interactions for Myricetin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Myricetin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id