DrugAge entry for Methylene blue

Name: Methylene blue
Synonyms: 61-73-4 • Basic blue 9 • Bleu de methylene • C.I. Basic Blue 9 • Calcozine Blue ZF • Chromosmon • External Blue 1 • methylene blue • Methylene Blue A • Methylene Blue anhydrous • Methylene Blue B • Methylene Blue BB • Methylene Blue BD • Methylene Blue BP • Methylene Blue BX • Methylene Blue BZ • Methylene Blue chloride • Methylene Blue D • Methylene Blue G • Methylene Blue N • Methylenium ceruleum • Methylthioninium chloride • Solvent blue 8 • Swiss Blue • Urolene blue
CAS Number: 61-73-4
IUPAC Name: [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride
PubChem CID: 6099

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Methylene blue

Average/Median Lifespan
Max Lifespan
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References

Harold R Massie (1993) Influence of photosensitizers and light on the life span of Drosophila Mechanisms of Ageing and Development 68(1-3)175-182 PubMed
Harrison, DE et al. (2014) Acarbose, 17-\u03b1-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell 13(2)273-282 PubMed

DGIdb Human Drug-Gene Interactions for Methylene blue

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Methylene blue

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id