DrugAge entry for Methionine

Name: Methionine
Synonyms: (L)-Methionine • (S)-2-Amino-4-(methylthio)butanoic acid • (S)-methionine • 63-68-3 • Acimethin • Cymethion • h-Met-h • h-Met-oh • L-(-)-Methionine • L-alpha-Amino-gamma-methylmercaptobutyric acid • L-Homocysteine, S-methyl- • L-Methionin • L-methionine • L-Methioninum • Liquimeth • Methilanin • methionine • Methionine (VAN) • Methioninum • Methioninum [INN-Latin] • metionina • Metionina [DCIT] • Neo-methidin • Polymethionine • S-Methionine
CAS Number: 63-68-3
IUPAC Name: (2S)-2-amino-4-methylsulfanylbutanoic acid
PubChem CID: 6137

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Methionine

Average/Median Lifespan
Max Lifespan
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References

Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed
Sharma SP (1995) Methionine-induced alterations in the life span, antioxidant enzymes, and peroxide levels in aging Zaprionus paravittiger (Diptera) Gerontology 41(2)86-93 PubMed
Harold R. Massie (1984) The effect of dietary methionine on the copper content of tissues and survival of young and old mice Experimental Gerontology 19(6)393-9 PubMed

DGIdb Human Drug-Gene Interactions for Methionine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Methionine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id