DrugAge entry for Lovastin

Name: Lovastin
Synonyms: 6-alpha-Methylcompactin • 6alpha-Methylcompactin • 75330-75-5 • Altocor • Altoprev • Artein • Hipovastin • Lovalip • Lovalord • lovastatin • Lovastatina [Spanish] • Lovastatine • Lovastatine [French] • Lovastatinum [Latin] • Mevacor • Mevinacor • mevinolin • MK-803 • Monacolin K • Nergadan
CAS Number: 75330-75-5
IUPAC Name: [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
PubChem CID: 53232

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Lovastin

Average/Median Lifespan
Max Lifespan
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References

Jahn, A et al. (2020) Statins Induce a DAF-16/Foxo-dependent Longevity Phenotype via JNK-1 through Mevalonate Depletion in Aging Dis 11(1)60-72 PubMed

DGIdb Human Drug-Gene Interactions for Lovastin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Lovastin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id