DrugAge entry for Kinetin

Name: Kinetin
Synonyms: 1H-PURIN-6-AMINE, N-(2-FURANYLMETHYL)- • 2-Furanmethanamine, N-1H-purin-6-yl- • 525-79-1 • 6-(Furfurylamino)purine • 6-Furfuryladenine • 6-Furfurylaminopurine • 9H-Purin-6-amine, N-(2-furanylmethyl)- • Adenine, N-furfuryl- • Caswell No. 272D • Cytex • Cytokinin • Furfuryl(purin-6-yl)amine • kinetin • Kinetin (plant hormone) • Kinetin (VAN) • N(sup 6)-Furfuryladenine • N-(2-Furanylmethyl)-1H-purin-6-amine • N-(furan-2-ylmethyl)-1H-purin-6-amine • N-(furan-2-ylmethyl)-7H-purin-6-amine • N-(furan-2-ylmethyl)-9H-purin-6-amine • N-Furfuryladenine • N6-(Furfurylamino)purine • N6-Furfuryladenine • NSC 23119 • UNII-P39Y9652YJ
CAS Number: 525-79-1
IUPAC Name: N-(furan-2-ylmethyl)-7H-purin-6-amine
PubChem CID: 3830
SEP-L1000 side effects: Abdominal pain, Body temperature increased, Diarrhoea, Dizziness, Dyspepsia, Erythema, Headache, Hypersensitivity, Nausea, Oedema, Pain, Paraesthesia, Pruritus, Rash, Somnolence, Urticaria, Vomiting

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Kinetin

Average/Median Lifespan
Max Lifespan
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References

Sharma, SP et al. (1995) Plant growth hormone kinetin delays ageing, prolongs the lifespan and slows down development of the fruitfly Zaprionus paravittiger. Biochem. Biophys. Res. Commun. 216(3)1067-1071 PubMed
Suraj P. Sharma (1997) Increased longevity of kinetin-fed Zaprionus fruitflies is accompanied by their reduced fecundity and enhanced catalase activity Biochemistry and Molecular Biology International 41(5)869-75 PubMed
Kadlecová, A et al. (2018) Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology 19(2)109-120 PubMed

DGIdb Human Drug-Gene Interactions for Kinetin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Kinetin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id