DrugAge entry for Kinetin

Name
Kinetin 
Synonyms
1H-PURIN-6-AMINE, N-(2-FURANYLMETHYL)- • 2-Furanmethanamine, N-1H-purin-6-yl- • 525-79-1 • 6-(Furfurylamino)purine • 6-Furfuryladenine • 6-Furfurylaminopurine • 9H-Purin-6-amine, N-(2-furanylmethyl)- • Adenine, N-furfuryl- • Caswell No. 272D • Cytex • Cytokinin • Furfuryl(purin-6-yl)amine • kinetin • Kinetin (plant hormone) • Kinetin (VAN) • N(sup 6)-Furfuryladenine • N-(2-Furanylmethyl)-1H-purin-6-amine • N-(furan-2-ylmethyl)-1H-purin-6-amine • N-(furan-2-ylmethyl)-7H-purin-6-amine • N-(furan-2-ylmethyl)-9H-purin-6-amine • N-Furfuryladenine • N6-(Furfurylamino)purine • N6-Furfuryladenine • NSC 23119 • UNII-P39Y9652YJ 
CAS Number
525-79-1 
IUPAC Name
N-(furan-2-ylmethyl)-7H-purin-6-amine 
PubChem CID
3830 
SEP-L1000 side effects
Abdominal pain, Body temperature increased, Diarrhoea, Dizziness, Dyspepsia, Erythema, Headache, Hypersensitivity, Nausea, Oedema, Pain, Paraesthesia, Pruritus, Rash, Somnolence, Urticaria, Vomiting 

Summary

Species No. Entries MAX(Avg Lifespan Change %) MAX(Max Lifespan Change %)

Results

Compound/Formulation Species Avg/Med Lifespan Change (%) Max Lifespan Change (%) Strain Dosage Significant? Reference

Lifespan Charts for Kinetin


References

Sharma, SP et al. (1995) Plant growth hormone kinetin delays ageing, prolongs the lifespan and slows down development of the fruitfly Zaprionus paravittiger. Biochem. Biophys. Res. Commun. 216(3)1067-1071 PubMed
Suraj P. Sharma (1997) Increased longevity of kinetin-fed Zaprionus fruitflies is accompanied by their reduced fecundity and enhanced catalase activity Biochemistry and Molecular Biology International 41(5)869-75 PubMed
Kadlecová, A et al. (2018) Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology 19(2)109-120 PubMed

DGIdb Human Drug-Gene Interactions for Kinetin

Interaction Types Gene Symbol Common Name Entrez Id DGIdb Sources Homologs References

Stitch DB Human Drug-Protein Interactions for Kinetin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id