DrugAge entry for KT109

Name: KT109
Synonyms: (4-([1,1'-Biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)(2-benzylpiperidin-1-yl)methanone • (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[2-(phenylmethyl)-1-piperidinyl]-methanone • (R)-KT109 • (S)-KT109 • 1402612-55-8 • AKOS037643526 • AOB3993 • AS-16776 • BDBM50211236 • CHEMBL2144065 • GTPL10245 • KT-109 • Methanone, (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[2-(phenylMethyl)-1-piperidinyl]- • Methanone,(4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[2-(phenylMethyl)-1-piperidinyl]- • MLS004256813 • NCGC00408825-01 • SCHEMBL13192827 • SMR003081888 • SR-02000001744 • SR-02000001744-1
CAS Number
IUPAC Name: (2-benzylpiperidin-1-yl)-[4-(4-phenylphenyl)triazol-1-yl]methanone
PubChem CID: 53364540

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for KT109

Average/Median Lifespan
Max Lifespan
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References

Chen, AL et al. (2019) Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol 15(5)453-462 PubMed

DGIdb Human Drug-Gene Interactions for KT109

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for KT109

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id