The Human Ageing Genomic Resources are at risk. Please support our work at JustGiving.

DrugAge entry for JW1036

Name
JW1036 
Synonyms
2-(4-(tert-butyl)phenyl)-N-methyl-6-(p-tolyl)-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxamide (JW1036) • BDBM154537 
CAS Number
 
IUPAC Name
6-(4-tert-butylphenyl)-N-methyl-2-(4-methylphenyl)-1-(4-methylphenyl)sulfonyl-3,6-dihydro-2H-pyridine-5-carboxamide 
PubChem CID
91970626 

Summary

Species No. Entries MAX(Avg/Med Lifespan Change %) MEAN(Avg/Med Lifespan Change %) MAX(Max Lifespan Change %) MEAN(Max Lifespan Change %)

Results

Compound/Formulation Species Sex Strain Dosage Avg/Med Lifespan Change (%) Avg/Med Lifespan Significance Max Lifespan Change (%) Reference

Lifespan Charts for JW1036


References

Chen, AL et al. (2019) Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol 15(5)453-462 PubMed

DGIdb Human Drug-Gene Interactions for JW1036

Interaction Types Gene Symbol Common Name HGNC Id DGIdb Sources References

Stitch DB Human Drug-Protein Interactions for JW1036

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id