DrugAge entry for J147

Name: J147
Synonyms: 1146963-51-0 • 1807913-16-1 • 3752AH • Acetic acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-((3-methoxyphenyl)methylene)hydrazide • Acetic acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide • AKOS024458485 • C18H17F3N2O2 • CCG-268030 • CHEMBL2387144 • CS-3688 • DB13957 • EX-A2235 • HMS3886O17 • J 147 • J-147 • j147 • MFCD25976644 • N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-(3-methoxybenzylidene)acetohydrazide • s5269 • SB19600 • SCHEMBL12995834 • SCHEMBL21294999 • UNII-Z41H3C5BT9 • Z41H3C5BT9 • ZINC214323435
CAS Number: 1146963-51-0
IUPAC Name: N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide
PubChem CID: 25229652

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for J147

Average/Median Lifespan
Max Lifespan
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References

Goldberg, J et al. (2018) The mitochondrial ATP synthase is a shared drug target for aging and dementia Aging Cell () PubMed
Kepchia, D et al. (2021) Geroprotective effects of Alzheimer's disease drug candidates. Aging (Albany NY) 13(3)3269-3289 PubMed

DGIdb Human Drug-Gene Interactions for J147

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for J147

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id