DrugAge entry for INT-767d (FXR/TGR5 agonist)

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for INT-767d (FXR/TGR5 agonist)

Average/Median Lifespan
Max Lifespan
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References

Harrison, DE et al. (2019) Acarbose improves health and lifespan in aging HET3 mice. Aging Cell 18(2)e12898 PubMed

DGIdb Human Drug-Gene Interactions for INT-767d (FXR/TGR5 agonist)

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for INT-767d (FXR/TGR5 agonist)

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id