DrugAge entry for Hypotaurine

Name: Hypotaurine
Synonyms: 2-amino-Ethanesulfinate • 2-amino-Ethanesulfinic acid • 2-aminoethane-1-sulfinic acid • 2-Aminoethanesulfinic acid • 2-Aminoethylsulfinate • 2-Aminoethylsulfinic acid • 300-84-5 • 5L08GE4332 • ACMC-1CMF0 • bmse000452 • CHEBI:16668 • Cystaminesulfinate • Cystaminesulfinic acid • Ethanesulfinic acid, 2-amino- • Hypotaurine, >=98% (TLC) • Lopac-H-1384 • Lopac0_000573 • SCHEMBL154548 • Tocris-0208 • UNII-5L08GE4332
CAS Number: 300-84-5
IUPAC Name: 2-aminoethanesulfinic acid
PubChem CID: 107812

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Hypotaurine

Average/Median Lifespan
Max Lifespan
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References

Wan, QL et al. (2020) Hypotaurine promotes longevity and stress tolerance via the stress response factors DAF-16/FOXO and SKN-1/NRF2 in Caenorhabditis elegans. Food Funct 11(1)347-357 PubMed
Harold R Massie (1989) Changes in taurine in aging fruit flies and mice Experimental Gerontology 24(1)57-65 PubMed

DGIdb Human Drug-Gene Interactions for Hypotaurine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Hypotaurine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id