DrugAge entry for Hydroxyprogesterone caproate

Name: Hydroxyprogesterone caproate
Synonyms: 17-Caproxyprogesterone • 17alpha-Hydroxyprogesterone caproate • 630-56-8 • Delalutin • Depo-Proluton • Duraluton • Estralutin • Hormofort • HYDROXYPROGESTERONE CAPROATE • Hydroxyprogesterone hexanoate • Hylutin • Hyproval • Hyroxon • Idrogestene • Kaprogest • Lutate • Luteocrin • Lutopron • Neolutin • Neolutin forte • Primolut Depot • Proge • Progesterone caproate • Proluton Depot • Relutin • Syngynon • Teralutil
CAS Number: 630-56-8
IUPAC Name: [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate
PubChem CID: 169870

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Hydroxyprogesterone caproate

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Hydroxyprogesterone caproate

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Hydroxyprogesterone caproate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id