DrugAge entry for Hispidol

Name: Hispidol
Synonyms: (2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one • (Z)-4',6-Dihydroxyaurone • 3(2H)-Benzofuranone, 6-hydroxy-2-((4-hydroxyphenyl)methylene)-, (2Z)- • 3(2H)-Benzofuranone, 6-hydroxy-2-[(4-hydroxyphenyl)methylene]-, (2Z)- • 4',6-Dihydroxyaurone • 5786-54-9 • 6,4' -dihydroxy aurone • 6,4''-DIHYDROXYAURONE • AB00767717-01 • AKOS001354021 • BDBM50180260 • C08644 • CHEBI:5731 • CHEMBL426110 • CS-7503 • CS1235I0WT • Hispidol • HY-102040 • Isoliquiritigenin metabolite M6 • NSC-356828 • NSC356828 • SCHEMBL5707753 • UNII-CS1235I0WT • ZE-Hispidol • ZINC13481340
CAS Number: 5786-54-9
IUPAC Name: (2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one
PubChem CID: 5281254

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Hispidol

Average/Median Lifespan
Max Lifespan
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References

Lim, HJ et al. (2020) Longevity effects of hispidol in Caenorhabditis elegans. Biofactors 46(6)1041-1048 PubMed

DGIdb Human Drug-Gene Interactions for Hispidol

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Hispidol

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id