DrugAge entry for Glycine

Name: Glycine
Synonyms: 2-Aminoacetic acid • 56-40-6 • Acetic acid, amino- • Aciport • aminoacetic acid • Aminoazijnzuur • Aminoethanoic acid • Amitone • Corilin • Glicoamin • GLY (IUPAC abbrev) • glycine • Glycine, non-medical • Glycinum • Glycocoll • Glycolixir • Glycosthene • Gyn-hydralin • H-Gly-OH • Hampshire glycine • L-Glycine • Leimzucker • Padil • polyglycine • Sucre de gelatine
CAS Number: 56-40-6
IUPAC Name: 2-aminoacetic acid
PubChem CID: 750

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Glycine

Average/Median Lifespan
Max Lifespan
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References

Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed
Liu, YJ et al. (2019) Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion. PLoS Genet 15(3)e1007633 PubMed
Miller, RA et al. (2019) Glycine supplementation extends lifespan of male and female mice. Aging Cell 18(3)e12953 PubMed

DGIdb Human Drug-Gene Interactions for Glycine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Glycine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id