DrugAge entry for Glutathione

Name: Glutathione
Synonyms: 70-18-8 • Agifutol S • Copren • Deltathione • Glutathion • glutathione • Glutathione (reduced) • Glutathione SH • Glutathione-SH • Glutatiol • Glutatione • Glutide • Glutinal • GSH • Isethion • L-Glutathione • L-Glutathione reduced • L-Glutatione • Ledac • Neuthion • Panaron • reduced glutathione • Tathion • Tathione • Triptide
CAS Number: 98726-08-0
IUPAC Name: (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
PubChem CID: 124886

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Glutathione

Average/Median Lifespan
Max Lifespan
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References

Shibamura, A et al. (2009) A method for oral administration of hydrophilic substances to Caenorhabditis elegans: Effects of oral supplementation with antioxidants on the nematode lifespan. Mech. Ageing Dev. 130(9)652-655 PubMed
Ivan Gusarov (2021) Dietary thiols accelerate aging of C. elegans Nature Communications 12(1)4336 PubMed

DGIdb Human Drug-Gene Interactions for Glutathione

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Glutathione

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id