DrugAge entry for Gluconic acid

Name: Gluconic acid
Synonyms: (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid • 2,3,4,5,6-Pentahydroxyhexanoic acid • 526-95-4 • BRN 1726055 • C6H12O7 • D-Gluco-hexonic acid • D-gluconate • D-gluconic acid • D-Gluconsaeure • D-Glukonsaeure • dextronic acid • EINECS 208-401-4 • Glosanto • gluconate • gluconic acid • Gluconic acid (VAN) • Gluconic acid, D- • Glycogenic acid • Glyconic acid • HSDB 487 • maltonic acid • NSC 77381 • Pentahydroxycaproic acid • R4R8J0Q44B • UNII-R4R8J0Q44B
CAS Number: 133-42-6
IUPAC Name: (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid
PubChem CID: 10690

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Gluconic acid

Average/Median Lifespan
Max Lifespan
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References

Massie, HR and Williams, TR (1979) Increased longevity of Drosophila melanogaster with lactic and gluconic acids. Exp. Gerontol. 14(3)109-115 PubMed
Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed

DGIdb Human Drug-Gene Interactions for Gluconic acid

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Gluconic acid

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id