DrugAge entry for Fluprednisolone

Name: Fluprednisolone
Synonyms: (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one • 53-34-9 • 6-alpha-Fluoroprednisolone • 6alpha-Fluoroprednisolone • 9H05937G3X • Alphadrol • B 673 • CHEBI:34474 • DSSTox_CID_26067 • DSSTox_RID_81317 • Etadrol • F. I. 6150 • Isopredon • NCGC00182067-02 • NSC 47439 • Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-, (6alpha,11beta)- • U 7800 • U-7800 • UNII-9H05937G3X • Vladicort
CAS Number: 53-34-9
IUPAC Name: (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
PubChem CID: 5876

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Fluprednisolone

Average/Median Lifespan
Max Lifespan
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References

Hochschild, R. (1971) Effect of membrane stabilizing drugs on mortality in Drosophila melanogaster. Exp Gerontol 6(2)133-151 PubMed

DGIdb Human Drug-Gene Interactions for Fluprednisolone

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Fluprednisolone

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id