DrugAge entry for Ferulic Acid

Name: Ferulic Acid
Synonyms: (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid • (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid • (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid • (E)-4'-Hydroxy-3'-methoxycinnamic acid • (E)-4-Hydroxy-3-methoxycinnamic acid • (E)-Ferulic acid • 1135-24-6 • 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)- • 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid • 3-(4-Hydroxy-3-methoxyphenyl)acrylic acid • 3-methoxy-4-hydroxycinnamic acid • 4-Hydroxy-3-methoxy cinnamic acid • 4-Hydroxy-3-methoxycinnamic acid • 537-98-4 • Cinnamic acid, 4-hydroxy-3-methoxy- • Cinnamic acid, 4-hydroxy-3-methoxy-, (E)- • Coniferic acid • ferulate • ferulic acid • Ferulic acid, trans- • Fumalic acid • MFCD00004400 • trans-4-Hydroxy-3-methoxycinnamic acid • trans-Ferulic Acid • UNII-AVM951ZWST
CAS Number: 537-98-4
IUPAC Name: (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
PubChem CID: 445858

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Ferulic Acid

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Li, H et al. (2021) Ferulic Acid Supplementation Increases Lifespan and Stress Resistance via Insulin/IGF-1 Signaling Pathway in Int J Mol Sci 22(8) PubMed

DGIdb Human Drug-Gene Interactions for Ferulic Acid

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Ferulic Acid

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id