DrugAge entry for Ethotoin

Name: Ethotoin
Synonyms: (+-)-3-Ethyl-5-phenylhydantoin • 1-Ethyl-2,5-dioxo-4-phenylimidazolidine • 2,4-Imidazolidinedione, 3-ethyl-5-phenyl- • 3-Ethyl-5-phenyl-2,4-imidazolidinedione • 3-ethyl-5-phenyl-imidazolidine-2,4-dione • 3-Ethyl-5-phenylhydantoin • 3-Ethyl-5-phenylimidazolidin-2,4-dione • 3-ethyl-5-phenylimidazolidine-2,4-dione • 86-35-1 • AC-695; Accenon • Accenon • Accenon (TN) • CHEBI:4888 • ethotoin • ETHOTOIN (200 MG) • Ethotoine • Ethotoine [INN-French] • Ethotoinum • Ethotoinum [INN-Latin] • Etotoina • Etotoina [INN-Spanish] • HSDB 3580 • Hydantoin, 3-ethyl-5-phenyl- • Peganone • Peganone (TN) • Pegoanone
CAS Number: 86-35-1
IUPAC Name: 3-ethyl-5-phenylimidazolidine-2,4-dione
PubChem CID: 3292

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Ethotoin

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Ethotoin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Ethotoin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id