DrugAge entry for Ethopropazine Hydrochloride

Name: Ethopropazine Hydrochloride
Synonyms: 10-(2-(Diethylamino)propyl)phenothiazine monohydrochloride • 1094-08-2 • CHEBI:31568 • CHEMBL1200970 • Dibutil • DSSTox_CID_25347 • DSSTox_GSID_45347 • DSSTox_RID_80815 • Ethopropazine HCl • Ethopropazine hydrochloride • ethopropazine monohydrochloride • Isothazine hydrochloride • Lysivane • N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride • N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride • N,N-Diethyl-alpha-methyl-10H-phenothiazine-10-ethylamine monohydrochloride • Pardisol • Parfezin • Parphezein • Parphezin • Parsidol hydrochloride • Parsidol monohydrochloride • Profenamine HCl • Profenamine hydrochloride • Profenamine monohydrochloride
CAS Number: 42957-54-0
IUPAC Name: N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride
PubChem CID: 122824

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Ethopropazine Hydrochloride

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Ethopropazine Hydrochloride

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Ethopropazine Hydrochloride

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id