DrugAge entry for Ethopropazine

Name: Ethopropazine
Synonyms: 522-00-9 • Ethapropazine • Ethopromazine • Fempropazine • Isopthazine • Isothazine • Isothiazine • Parfezine • Parkin • Parsidol • Parsitan • Parsotil • Phenopropazine • Profenamina • Profenamina [Italian] • Profenamine • Profenaminum • Prophenamine • Prophenaminum • Rodipal
CAS Number: 522-00-9
IUPAC Name: N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine
PubChem CID: 3290

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Ethopropazine

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Ethopropazine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Ethopropazine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id