DrugAge entry for Epitalon

Name: Epitalon
Synonyms: (4S)-4-[(2S)-2-AMINOPROPANAMIDO]-4-{[(1S)-2-CARBOXY-1-(CARBOXYMETHYLCARBAMOYL)ETHYL]CARBAMOYL}BUTANOIC ACID • (4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-1-(carboxymethylamino)-4-hydroxy-1,4-dioxobutan-2-yl]amino]-5-oxopentanoic acid • 307297-39-8 • 64082-79-7 • AC1L55Y7 • AC1Q5OK4 • AM022085 • BDM-E • D07JRL • Epitalon • Epitalon (Russian Academy of Medical Sciences) • Epithalamin • Epithalamine • Epithalon • FT-0773207 • Glycine, L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl- • L-Alanyl-L-&Alpha • L-Alanyl-L-glutamyl-L-aspartyl-glycine • l-alanyl-l-|A-glutamyl-l-|A-aspartylglycine • LS-72251 • O65P17785G • Retinal disease therapeutic, Biodiem • SCHEMBL5685928 • UNII-O65P17785G • ZINC3966198
CAS Number: 64082-79-7
IUPAC Name: Ala-Glu-Asp-Gly
PubChem CID: 219042

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Epitalon

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Khavinson, VK et al. (2000) Effect of epitalon on the lifespan increase in Drosophila melanogaster. Mech. Ageing Dev. 120(1-3)141-149 PubMed
Anisimov, VN et al. (2003) Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology 4(4)193-202 PubMed

DGIdb Human Drug-Gene Interactions for Epitalon

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Epitalon

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id