DrugAge entry for Enoxacin

Name: Enoxacin
Synonyms: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid • 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid • 74011-58-8 • Almitil • AT-2266 • Bactidan • CI 919 • CI-919 • Comprecin • enofloxacin • Enoksetin • Enoram • enoxacin • Enoxacin (Penetrex) • Enoxacine • Enoxacine [French] • Enoxacino • Enoxacino [Spanish] • Enoxacinum • Enoxacinum [Latin] • Enoxin • Enoxor • Flumark • PD 107779 • Penetrex
CAS Number: 74011-58-8
IUPAC Name
PubChem CID
SEP-L1000 side effects: Abdominal pain, Arthralgia, Asthenia, Body temperature increased, Constipation, Convulsion, Decreased appetite, Diarrhoea, Dizziness, Dyspepsia, Dyspnoea, Fatigue, Headache, Hypersensitivity, Leukopenia, Malaise, Myalgia, Nausea, Oedema, Pain, Pharyngitis, Pruritus, Rash, Somnolence, Tachycardia, Thrombocytopenia, Urticaria, Vomiting

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Enoxacin

Average/Median Lifespan
Max Lifespan
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References

Pinto S, et al. (2018) Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis Redox biology () PubMed

DGIdb Human Drug-Gene Interactions for Enoxacin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Enoxacin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id