DrugAge entry for Emodin

Name: Emodin
Synonyms: 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione • 1,3,8-Trihydroxy-6-methyl-9,10-anthraquinone • 1,3,8-trihydroxy-6-methylanthracene-9,10-dione • 1,3,8-Trihydroxy-6-methylanthraquinone • 3-Methyl-1,6,8-trihydroxyanthraquinone • 4,5,7-Trihydroxy-2-methylanthraquinone • 518-82-1 • 6-Methyl-1,3,8-trihydroxyanthraquinone • 9,10-Anthracenedione, 1,3,8-trihydroxy-6-methyl- • Alatinone • Anthraquinone, 1,3,8-trihydroxy-6-methyl- • Archin • C.I. 75440 • C.I. Natural Yellow 14 • CCRIS 3528 • emodin • Emodol • Frangula emodin • Frangulic acid • Frangulinic acid • HSDB 7093 • NSC 408120 • NSC 622947 • Persian Berry Lake • Rheum emodin • Rheum-emodin • Schuttgelb • UNII-KA46RNI6HN
CAS Number: 518-82-1
IUPAC Name: 1,3,8-trihydroxy-6-methylanthracene-9,10-dione
PubChem CID: 3220
SEP-L1000 side effects: Abdominal pain, Anaphylactic shock, Asthenia, Body temperature increased, Constipation, Cough, Decreased appetite, Diarrhoea, Dizziness, Dyspepsia, Headache, Hyperhidrosis, Hypersensitivity, Infection, Insomnia, Malaise, Nausea, Oedema, Pain, Paraesthesia, Pruritus, Rash, Urticaria, Vomiting

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Emodin

Average/Median Lifespan
Max Lifespan
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References

Smita SS, et al. (2017) Shatavarin IV elicits lifespan extension and alleviates Parkinsonism in Caenorhabditis elegans Free radical research () PubMed

DGIdb Human Drug-Gene Interactions for Emodin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Emodin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id