DrugAge entry for Echinacoside

Name: Echinacoside
Synonyms: 82854-37-3 • AC1NQZ1Q • C35H46O20 • CHEBI:4745 • CHEMBL510539 • DSSTox_CID_13469 • DSSTox_GSID_33469 • DSSTox_RID_79077 • DTXSID0033469 • Echinacoside • Echinacoside, 98% (HPLC) • Echinacoside, analytical standard • Echinacoside,(S) • Echinacoside; • Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl-(1-3)-O-(beta-D-glucopyranosyl-(1-6))-, 4-(3-(3,4-dihydroxyphenyl)-2-propenoate), beta-D- • HY-N0020 • I04O1DT48T • MEGxp0_001773 • MFCD00075695 • MolPort-001-742-524 • SCHEMBL525502 • SureCN525502 • Tox21_200945 • UNII-I04O1DT48T • [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
CAS Number: 82854-37-3
IUPAC Name: [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
PubChem CID: 5281771

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Echinacoside

Average/Median Lifespan
Max Lifespan
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References

Wang X,. () The longevity effect of echinacoside in Caenorhabditis elegans mediated through daf-16. Biosci Biotechnol Biochem () PubMed
Zhou L, et al. (2017) Arbutin increases Caenorhabditis elegans longevity and stress resistance PeerJ () PubMed

DGIdb Human Drug-Gene Interactions for Echinacoside

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Echinacoside

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id