DrugAge entry for EUK-134

Name: EUK-134
Synonyms: 81065-76-1 • A840029 • AKOS015914965 • AN-36301 • CE-851 • EUK 134 • EUK-134 • FT-0655530 • I14-7464 • MANGANESE(2+) ION 2-METHOXY-6-{[(2-{[(3-METHOXY-2-OXIDOPHENYL)METHYLIDENE]AMINO}ETHYL)IMINO]METHYL}BENZENOLATE CHLORIDE • manganese(2+); 2-methoxy-6-[2-[(3-methoxy-2-oxidanidyl-phenyl)methylideneamino]ethyliminomethyl]phenolate; chloride • manganese(2+); 2-methoxy-6-[2-[(3-methoxy-2-oxidophenyl)methylideneamino]ethyliminomethyl]phenolate; chloride • manganous 2-methoxy-6-[2-[(3-methoxy-2-oxido-phenyl)methyleneamino]ethyliminomethyl]phenolate chloride • OR072712
CAS Number: 81065-76-1
IUPAC Name: manganese(2+);2-methoxy-6-[2-[(3-methoxy-2-oxidophenyl)methylideneamino]ethyliminomethyl]phenolate;chloride
PubChem CID: 45489809

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for EUK-134

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Melov, S et al. (2000) Extension of life-span with superoxide dismutase/catalase mimetics. Science 289(5484)1567-1569 PubMed
Canistro, D et al. (2015) Redox-Based Flagging of the Global Network of Oxidative Stress Greatly Promotes Longevity. J. Gerontol. A Biol. Sci. Med. Sci. 70(8)936-943 PubMed

DGIdb Human Drug-Gene Interactions for EUK-134

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for EUK-134

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id