DrugAge entry for EGTA

Name: EGTA
Synonyms: 1,2-Bis(2-dicarboxymethylaminoethoxy)ethane • 1,2-Bis[2-[bis(carboxymethyl)amino]ethoxy]ethane • 6,9-Dioxa-3,12-diazatetradecanedioic acid, 3,12-bis(carboxymethyl)- • 67-42-5 • Acide egtazique [INN-French] • Acido egtazico [INN-Spanish] • Acidum egtazicum [INN-Latin] • C14H24N2O10 • Ebonta • EGTA • Egtazic acid • Ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid • Ethylene glycol bis(2-aminoethyl ether)tetraacetic acid • Ethylene Glycol Tetraacetic Acid • Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid • Ethylenebis(oxyethylenenitrilo)tetraacetic acid • Ethylenedioxybis(ethyleneamino)tetraacetic acid • Gedta • Glycol-etherdiaminetetraacetic acid • Glycoletherdiaminetetraacetic Acid • H4egta • NSC 615010 • Tetrasodium EGTA • UNII-526U7A2651 • [Ethylenebis(oxyethylenenitrilo)]tetraacetic acid
CAS Number: 67-42-5
IUPAC Name: 2-[2-[2-[2-[bis(carboxymethyl)amino]ethoxy]ethoxy]ethyl-(carboxymethyl)amino]acetic acid
PubChem CID: 6207

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for EGTA

Average/Median Lifespan
Max Lifespan
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References

Sincock, AM. (1975) Life extension in the rotifer Mytilina brevispina var redunca by the application of chelating agents. J Gerontol 30(3)289-293 PubMed
Hildegard E. Enesco (1980) Effect of calcium, magnesium and chelating agents on the lifespan of the rotifer Asplanchna brightwelli Experimental Gerontology 15(5)389-392 PubMed

DGIdb Human Drug-Gene Interactions for EGTA

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for EGTA

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id