DrugAge entry for Disulfiram

Name
Disulfiram 
Synonyms
97-77-8 • Abstensil • Abstinil • Abstinyl • Alcophobin • Antabus • Antabuse • Antaethyl • Anticol • Antietanol • Antivitium • Bis(diethylthiocarbamoyl) disulfide • Contralin • Dicupral • disulfiram • Esperal • Ethyldithiurame • Exhorran • Hoca • TETD • Tetradine • Tetraethylthiuram disulfide • Tetraetil • Teturam • Teturamin 
CAS Number
97-77-8 
IUPAC Name
 
PubChem CID
 
SEP-L1000 side effects
Death, Dermatitis, Dermatitis atopic, Dysgeusia, Erectile dysfunction, Fatigue, Headache, Hepatic failure, Hepatitis, Hepatitis fulminant, Neuritis, Neuropathy peripheral, Optic neuritis, Polyneuropathy, Psychotic disorder, Rash, Somnolence 

Summary

Species No. Entries MAX(Avg Lifespan Change %) MAX(Max Lifespan Change %)

Results

Compound/Formulation Species Avg/Med Lifespan Change (%) Max Lifespan Change (%) Strain Dosage Significant? Reference

Lifespan Charts for Disulfiram


References

Holck HG, et al. (1970) Effects of disulfiram on growth, longevity, and reproduction of the albino rat Journal of pharmaceutical sciences () PubMed

DGIdb Human Drug-Gene Interactions for Disulfiram

Interaction Types Gene Symbol Common Name Entrez Id DGIdb Sources Homologs References

Stitch DB Human Drug-Protein Interactions for Disulfiram

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id