The Human Ageing Genomic Resources are at risk. Please support our work at JustGiving.

DrugAge entry for Disulfiram

Name
Disulfiram 
Synonyms
97-77-8 • Abstensil • Abstinil • Abstinyl • Alcophobin • Antabus • Antabuse • Antaethyl • Anticol • Antietanol • Antivitium • Bis(diethylthiocarbamoyl) disulfide • Contralin • Dicupral • disulfiram • Esperal • Ethyldithiurame • Exhorran • Hoca • TETD • Tetradine • Tetraethylthiuram disulfide • Tetraetil • Teturam • Teturamin 
CAS Number
97-77-8 
IUPAC Name
 
PubChem CID
 
SEP-L1000 side effects
Death, Dermatitis, Dermatitis atopic, Dysgeusia, Erectile dysfunction, Fatigue, Headache, Hepatic failure, Hepatitis, Hepatitis fulminant, Neuritis, Neuropathy peripheral, Optic neuritis, Polyneuropathy, Psychotic disorder, Rash, Somnolence 

Summary

Species No. Entries MAX(Avg/Med Lifespan Change %) MEAN(Avg/Med Lifespan Change %) MAX(Max Lifespan Change %) MEAN(Max Lifespan Change %)

Results

Compound/Formulation Species Sex Strain Dosage Avg/Med Lifespan Change (%) Avg/Med Lifespan Significance Max Lifespan Change (%) Reference

Lifespan Charts for Disulfiram


References

Holck HG, et al. (1970) Effects of disulfiram on growth, longevity, and reproduction of the albino rat Journal of pharmaceutical sciences () PubMed

DGIdb Human Drug-Gene Interactions for Disulfiram

Interaction Types Gene Symbol Common Name HGNC Id DGIdb Sources References

Stitch DB Human Drug-Protein Interactions for Disulfiram

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id