DrugAge entry for Diphenhydramine HCl

Name: Diphenhydramine HCl
Synonyms: 147-24-0 • Allergan • Allergival • Ambenyl • Bena • Bendylate • Carphenamine • Carphenex • Cathejell • Denydryl • Dimedrol • Diphamine • DIPHENHYDRAMINE HYDROCHLORIDE • Eldadryl • Felben • Fenylhist • Noctomin • Paradryl • Prodryl • Restamin
CAS Number: 147-24-0
IUPAC Name: 2-benzhydryloxy-N,N-dimethylethanamine;hydrochloride
PubChem CID: 8980

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Diphenhydramine HCl

Average/Median Lifespan
Max Lifespan
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References

Hochschild, R. (1971) Effect of membrane stabilizing drugs on mortality in Drosophila melanogaster. Exp Gerontol 6(2)133-151 PubMed

DGIdb Human Drug-Gene Interactions for Diphenhydramine HCl

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Diphenhydramine HCl

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id