DrugAge entry for D-glucosamine

Name: D-glucosamine
Synonyms: (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol • 2-Amino-2-Deoxy-D-Glucopyranose • 2-Amino-2-Deoxy-D-Glucopyranoside • 2-Amino-2-Deoxy-D-Glucose • 2-Amino-2-Deoxy-Glucopyranose • 2-Amino-2-Deoxy-Glucopyranoside • 2-Amino-2-Deoxy-Glucose • 2-amino-2-deoxyglucose • 2-Aminoglucose • 2-Deoxy-2-Amino-D-Glucopyranose • 2-Deoxy-2-Amino-D-Glucopyranoside • 2-Deoxy-2-Amino-D-Glucose • 2-Deoxy-2-Amino-Glucopyranose • 2-Deoxy-2-Amino-Glucopyranoside • 2-Deoxy-2-Amino-Glucose • CHEBI:47977 • chitosamine • D-(+)-Glucosamine • D-GlcN • D-Glucosamine • D-Glucose, 2-amino-2-deoxy- • GlcN • Glucosamine • MSWZFWKMSRAUBD-IVMDWMLBSA-N • STK801823
CAS Number: 90-77-7
IUPAC Name: (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
PubChem CID: 2723635

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for D-glucosamine

Average/Median Lifespan
Max Lifespan
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References

Kaeberlein, M and Guarente, L (2002) Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity. Genetics 160(1)83-95 PubMed
Weimer, S et al. (2014) D-Glucosamine supplementation extends life span of nematodes and of ageing mice. Nat Commun 5()3563 PubMed

DGIdb Human Drug-Gene Interactions for D-glucosamine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for D-glucosamine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id