DrugAge entry for Cyclizine HCl

Name: Cyclizine HCl
Synonyms: (+-)-1-Diphenylmethyl-4-methylpiperazine hydrochloride • 1-(Diphenylmethyl)-4-methylpiperazine monohydrochloride • 1-benzhydryl-4-methyl-piperazine • 1-benzhydryl-4-methylpiperazine;hydrochloride • 303-25-3 • CHEBI:51045 • Cyclizine chloride • Cyclizine hydrochloride • cyclizine monohydrochloride • Dihydrochlorid • Echnatol • Fortravel • Marezine hydrochloride • Marzine • N-Benzhydryl-N'-methylpiperazine monohydrochloride • Piperazine, 1-(diphenylmethyl)-4-methyl-, monohydrochloride • Reis-fit • UNII-W0O1NHP4WE • Valoid • W0O1NHP4WE
CAS Number: 303-25-3
IUPAC Name: 1-benzhydryl-4-methylpiperazine;hydrochloride
PubChem CID: 6420019

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Cyclizine HCl

Average/Median Lifespan
Max Lifespan
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References

Hochschild, R. (1971) Effect of membrane stabilizing drugs on mortality in Drosophila melanogaster. Exp Gerontol 6(2)133-151 PubMed

DGIdb Human Drug-Gene Interactions for Cyclizine HCl

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Cyclizine HCl

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id