DrugAge entry for Colchine

Name: Colchine
Synonyms: (+-)-COLCHICINE • (R/S)-Colchicine • (S)-(-)-colchicine • (S)-Colchicine >95% • 209810-38-8 • 54192-66-4 • 64-86-8 • Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)- • Acetamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]- • CHEBI:23359 • CHEMBL87 • COLCHICINE, (+)- • Colchicine-[d3] • DTXSID20274387 • Epitope ID:141498 • MLS001181527 • N-(1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide • N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide • Neuro_000002 • SCHEMBL675246
CAS Number: 54192-66-4
IUPAC Name: N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
PubChem CID: 2833

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Colchine

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Hochschild, R. (1971) Effect of membrane stabilizing drugs on mortality in Drosophila melanogaster. Exp Gerontol 6(2)133-151 PubMed

DGIdb Human Drug-Gene Interactions for Colchine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Colchine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id