DrugAge entry for Clofilium Tosylate

Name: Clofilium Tosylate
Synonyms: 13ZVF1051K • 4-(4-chlorophenyl)butyl-diethyl-heptylazanium;4-methylbenzenesulfonate • 4-Chloro-N,N-Diethyl-N-Heptyl-Benzenebutanaminiusaltwith4-Methylbenzenes • 4-Chloro-N,N-diethyl-N-heptylbenzenebutanaminium tosylate • 92953-10-1 • ACMC-20ei9v • Benzenebutanaminium, 4-chloro-N,N-diethyl-N-heptyl-, salt with 4-methylbenzenesulfonicacid (1:1) • CAS-92953-10-1 • CHEMBL598270 • Clofilium tosylate • Clofilium tosylate, >97%, solid • DSSTox_CID_25601 • DSSTox_GSID_45601 • DSSTox_RID_80994 • DTXSID7045601 • GNF-Pf-3889 • HMS1568P20 • MFCD00069233 • MLS002154263 • N-(4-(4-Chlorophenyl)butyl)-N,N-diethylheptan-1-aminium 4-methylbenzenesulfonate • NCGC00017142-01 • Prestwick_682 • SCHEMBL467251 • SMR001233522 • UNII-13ZVF1051K
CAS Number: 92953-10-1
IUPAC Name: 4-(4-chlorophenyl)butyl-diethyl-heptylazanium;4-methylbenzenesulfonate
PubChem CID: 175533

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Clofilium Tosylate

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Clofilium Tosylate

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Clofilium Tosylate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id