DrugAge entry for Citrate

Name: Citrate
Synonyms: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, ion(3-) • 126-44-3 • 2-hydroxy-1,2,3-propanetricarboxylate • 2-Hydroxy-1,2,3-propanetricarboxylate(3-) • 2-hydroxypropane-1,2,3-tricarboxylate • 2-hydroxytricarballylate • 2qpq • 2yg2 • 3itc • 3kgq • 3r69 • 3ry8 • 4eu3 • AC1L1LG8 • ANION STANDARD - CITRATE • BDBM92494 • CHEBI:16947 • cit(3-) • citr • citrate • CITRATE ANION • citrate(3-) • CTK1A1286 • DTXSID30155037 • KRKNYBCHXYNGOX-UHFFFAOYSA-K
CAS Number: 126-44-3
IUPAC Name: 2-hydroxypropane-1,2,3-tricarboxylate
PubChem CID: 31348

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Citrate

Average/Median Lifespan
Max Lifespan
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References

Sincock, AM. (1975) Life extension in the rotifer Mytilina brevispina var redunca by the application of chelating agents. J Gerontol 30(3)289-293 PubMed
Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed

DGIdb Human Drug-Gene Interactions for Citrate

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Citrate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id