DrugAge entry for Catechin
- Name
- Catechin
- Synonyms
- (+)-catechin • (+)-Catechin Hydrate • (+)-Catechol • (+)-Cyanidan-3-ol • (+)-Cyanidanol • (2R,3S)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol • (2R,3S)-Catechin • 154-23-4 • 3-Cyanidanol, (+)- • Biocatechin • CATECHIN • Catechin (flavan) • Catechinic acid • Catechol (flavan) • Catechu • Catechuic acid • Catergen • Cianidanol • Cianidanolum • Cianidol • Cyanidanol • D-(+)-Catechin • D-Catechin • D-Catechol • Dexcyanidanol
- CAS Number
- 154-23-4
- IUPAC Name
- (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
- PubChem CID
- 9064
- SEP-L1000 side effects
- Abdominal pain, Asthenia, Decreased appetite, Diarrhoea, Dizziness, Dyspnoea, Erythema, Fatigue, Headache, Hyperhidrosis, Malaise, Nausea, Oedema, Pain, Paraesthesia, Pruritus, Rash, Somnolence, Tachycardia, Urticaria, Vomiting
Summary
| Species | No. Entries | MAX(Avg/Med Lifespan Change %) | MEAN(Avg/Med Lifespan Change %) | MAX(Max Lifespan Change %) | MEAN(Max Lifespan Change %) |
|---|
Results
| Compound/Formulation | Species | Sex | Strain | Dosage | Avg/Med Lifespan Change (%) | Avg/Med Lifespan Significance | Max Lifespan Change (%) | Reference |
|---|
Lifespan Charts for Catechin
- Average/Median Lifespan
- Max Lifespan
- Hide Charts
References
Massie, HR et al. (1993) Inhibition of iron absorption prolongs the life span of Drosophila. Mech. Ageing Dev. 67(3)227-237 PubMedSaul, N et al. (2009) Catechin induced longevity in C. elegans: from key regulator genes to disposable soma. Mech. Ageing Dev. 130(8)477-486 PubMed
Wu, X et al. (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11(6)5621-5634 PubMed
Saul, N et al. (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J. Nat. Prod. 74(8)1713-1720 PubMed
DGIdb Human Drug-Gene Interactions for Catechin
| Interaction Types | Gene Symbol | Common Name | HGNC Id | DGIdb Sources | References |
|---|---|---|---|---|---|
Stitch DB Human Drug-Protein Interactions for Catechin
Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.
| Ensembl Id | StringDB Id |
|---|