DrugAge entry for Carnosol

Name: Carnosol
Synonyms: (1R,8S,10S)-3,4-dihydroxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[6.6.2.01,10.02,7]hexadeca-2,4,6-trien-15-one • (4aR,9S,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-2,3,4,9,10,10a-hexahydro-1H-9,4a-(epoxymethano)phenanthren-12-one • 1,3,4,9,10,10aS-Hexahydro-5,6-dihydroxy-1,1-dimethyl-7-isopropyl-2H-9S,4aR-(epoxymethano)phenanthren-12-one • 483O455CKD • 5957-80-2 • BDBM50213683 • Carnosol, analytical standard • CCRIS 7122 • CHEBI:3429 • CHEMBL218693 • DTXSID80904451 • HSDB 7680 • HY-N0643 • MFCD02752467 • NSC 39143 • Picrosalvin • s9127 • SCHEMBL42365 • UNII-483O455CKD • ZINC3871891
CAS Number: 5957-80-2
IUPAC Name: (1R,8S,10S)-3,4-dihydroxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[6.6.2.01,10.02,7]hexadeca-2,4,6-trien-15-one
PubChem CID: 442009

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Carnosol

Average/Median Lifespan
Max Lifespan
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References

Lin, C et al. (2019) Carnosol Improved Lifespan and Healthspan by Promoting Antioxidant Capacity in Oxid Med Cell Longev 2019()5958043 PubMed

DGIdb Human Drug-Gene Interactions for Carnosol

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Carnosol

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id