DrugAge entry for Carnosine
- Name
- Carnosine
- Synonyms
- (2S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid • (2S)-2-(3-aminopropanoylamino)-3-imidazol-4-ylpropanoic acid • .beta.-Alanyl-L-histidine • 305-84-0 • beta-Alanyl-L-histidine • beta-Alanylhistidine • BRN 0087671 • Carnosine • CHEBI:15727 • CQOVPNPJLQNMDC-ZETCQYMHSA-N • EINECS 206-169-9 • Ignotine • Karnozin • Karnozzn • L-Carnosine • L-Histidine, beta-alanyl- • L-HISTIDINE, N-beta-ALANYL- • L-Ignotine • MFCD00005207 • N-2-M • N-beta-alanyl-L-histidine • Nalpha-(beta-alanyl)-L-histidine • NSC 524045 • ST057076 • UNII-8HO6PVN24W
- CAS Number
- 305-84-0
- IUPAC Name
- (2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid
- PubChem CID
- 439224
Summary
| Species | No. Entries | MAX(Avg/Med Lifespan Change %) | MEAN(Avg/Med Lifespan Change %) | MAX(Max Lifespan Change %) | MEAN(Max Lifespan Change %) |
|---|
Results
| Compound/Formulation | Species | Sex | Strain | Dosage | Avg/Med Lifespan Change (%) | Avg/Med Lifespan Significance | Max Lifespan Change (%) | Reference |
|---|
Lifespan Charts for Carnosine
- Average/Median Lifespan
- Max Lifespan
- Hide Charts
References
Yuneva, AO et al. (2002) Effect of carnosine on Drosophila melanogaster lifespan. Bull. Exp. Biol. Med. 133(6)559-561 PubMedStvolinsky, S et al. (2010) Effect of carnosine and its Trolox-modified derivatives on life span of Drosophila melanogaster. Rejuvenation Res 13(4)453-457 PubMed
Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed
Magdalena Kwolek-Mirek (2016) L-carnosine enhanced reproductive potential of the Saccharomyces cerevisiae yeast growing on medium containing glucose as a source of carbon Biogerontology 17()737–747 PubMed
DGIdb Human Drug-Gene Interactions for Carnosine
| Interaction Types | Gene Symbol | Common Name | HGNC Id | DGIdb Sources | References |
|---|---|---|---|---|---|
Stitch DB Human Drug-Protein Interactions for Carnosine
Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.
| Ensembl Id | StringDB Id |
|---|