DrugAge entry for Carnosine

Name
Carnosine 
Synonyms
(2S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid • (2S)-2-(3-aminopropanoylamino)-3-imidazol-4-ylpropanoic acid • .beta.-Alanyl-L-histidine • 305-84-0 • beta-Alanyl-L-histidine • beta-Alanylhistidine • BRN 0087671 • Carnosine • CHEBI:15727 • CQOVPNPJLQNMDC-ZETCQYMHSA-N • EINECS 206-169-9 • Ignotine • Karnozin • Karnozzn • L-Carnosine • L-Histidine, beta-alanyl- • L-HISTIDINE, N-beta-ALANYL- • L-Ignotine • MFCD00005207 • N-2-M • N-beta-alanyl-L-histidine • Nalpha-(beta-alanyl)-L-histidine • NSC 524045 • ST057076 • UNII-8HO6PVN24W 
CAS Number
305-84-0 
IUPAC Name
(2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid 
PubChem CID
439224 

Summary

Species No. Entries MAX(Avg Lifespan Change %) MAX(Max Lifespan Change %)

Results

Compound/Formulation Species Avg/Med Lifespan Change (%) Max Lifespan Change (%) Strain Dosage Significant? Reference

Lifespan Charts for Carnosine


References

Yuneva, AO et al. (2002) Effect of carnosine on Drosophila melanogaster lifespan. Bull. Exp. Biol. Med. 133(6)559-561 PubMed
Stvolinsky, S et al. (2010) Effect of carnosine and its Trolox-modified derivatives on life span of Drosophila melanogaster. Rejuvenation Res 13(4)453-457 PubMed
Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed

DGIdb Human Drug-Gene Interactions for Carnosine

Interaction Types Gene Symbol Common Name Entrez Id DGIdb Sources Homologs References

Stitch DB Human Drug-Protein Interactions for Carnosine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id