DrugAge entry for Carnosic acid

Name: Carnosic acid
Synonyms: (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-(propan-2-yl)-1,3,4,9,10,10a-hexahydrophenanthrene-4a(2H)-carboxylic acid • (4aR,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-4a-carboxylic Acid • 11,12-dihydroxy-13-isopropylpodocarpa-8,11,13-trien-17-oic acid • 11,12-dihydroxyabieta-8,11,13-trien-20-oic acid • 139236-75-2 • 3650-09-7 • Carnosic acid • Carnosic acid from Rosmarinus officinalis • Carnosic-acid • Carsonic acid • CHEBI:65585 • Deoxypicrosalvinic acid • LI791SXT24 • MFCD02259459 • NSC694080 • PubChem13039 • Rosamox • RoseOx • Salvin • UNII-LI791SXT24
CAS Number: 3650-09-7
IUPAC Name: (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-4a-carboxylic acid
PubChem CID: 65126

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Carnosic acid

Average/Median Lifespan
Max Lifespan
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References

Lin, C et al. (2019) Effects on longevity extension and mechanism of action of carnosic acid in Caenorhabditis elegans. Food Funct 10(3)1398-1410 PubMed

DGIdb Human Drug-Gene Interactions for Carnosic acid

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Carnosic acid

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id