DrugAge entry for Cardamonin

Name: Cardamonin
Synonyms: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one • (E)-1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-phenyl-propenone • (E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one • (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one • 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one • 18956-16-6 • 19309-14-9 • 2',4'-dihydroxy-6'-methoxychalcone • 2'4'-Dihydroxy-6'-methoxy-chalcone • 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-, (2E)- • Alpinetin chalcone • CARDAMOMIN • Cardamoni • Cardamonin ,(S) • CHEMBL378104 • Dihydroxymethoxychalcone • H8KP1OJ8JX • MLS000876992 • SCHEMBL449220 • UNII-H8KP1OJ8JX
CAS Number: 19309-14-9
IUPAC Name: (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
PubChem CID: 641785

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Cardamonin

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Cardamonin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Cardamonin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id