DrugAge entry for CASIN

Name: CASIN
Synonyms: 2-((6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino)ethan-1-ol • 2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol • 2-[(6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethan-1-ol • 2-[(6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethanol • 425399-05-9 • 6044-86-6 • AKOS024458473 • AOB2878 • BCP15785 • CASIN, >=98% (HPLC) • CB05449 • CBMicro_003660 • CHEMBL4303199 • DTXSID80387144 • EX-A3979 • MFCD01853271 • Oprea1_416851 • s6875 • SCHEMBL5454054 • SMSF0012088
CAS Number
IUPAC Name: 2-[(6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethanol
PubChem CID: 2882155

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for CASIN

Average/Median Lifespan
Max Lifespan
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References

Florian, MC et al. (2020) Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice. Aging Cell 19(9)e13208 PubMed

DGIdb Human Drug-Gene Interactions for CASIN

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for CASIN

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id