DrugAge entry for Bupivacaine Hydrochloride

Name: Bupivacaine Hydrochloride
Synonyms: (+-)-Bupivacaine hydrochloride • (S)-Bupivacaine hydrochloride • 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide monohydrochloride • 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride • 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide;hydrochloride • 14252-80-3 • 18010-40-7 • 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, hydrochloride (1:1) • AH-2250 • Bicain • Bloqueina • Bupivacaine (hydrochloride) • Bupivacaine HCL • Bupivacaine hydrochloride • Bupivacaine hydrochloride [JAN] • CHEBI:31322 • EINECS 241-917-8 • LAC-43 • Marcain • Marcaine Spinal • MNarcaine hydrochloride • SMR000058218 • Vivacaine • Win 11,318 • WIN-11318 • Xaracoll
CAS Number: 18010-40-7
IUPAC Name: 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide;hydrochloride
PubChem CID: 64737

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Bupivacaine Hydrochloride

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Bupivacaine Hydrochloride

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Bupivacaine Hydrochloride

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id