DrugAge entry for BIA 10-2474

Name: BIA 10-2474
Synonyms: 1233855-46-3 • 1H-Imidazole-1-carboxamide, N-cyclohexyl-N-methyl-4-(1-oxido-3-pyridinyl)- • 3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide • 5AP1ZW859M • BCP29970 • BDBM50505364 • BIA-10-2474 • BIA-102474 • BIA10-2474 • CHEMBL4460898 • compound 8 l [PubMed: 30113139] • CS-6218 • DTXSID901009325 • EX-A2490 • example 362 [WO2010074588] • GTPL9001 • N-cyclohexyl-N-methyl-4-(1-oxidopyridin-1-ium-3-yl)imidazole-1-carboxamide • SCHEMBL427970 • UNII-5AP1ZW859M • ZINC113812628
CAS Number: 1233855-46-3
IUPAC Name: N-cyclohexyl-N-methyl-4-(1-oxidopyridin-1-ium-3-yl)imidazole-1-carboxamide
PubChem CID: 46831476

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for BIA 10-2474

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Chen, AL et al. (2019) Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol 15(5)453-462 PubMed

DGIdb Human Drug-Gene Interactions for BIA 10-2474

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for BIA 10-2474

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id