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DrugAge entry for Azacytidine

Name
Azacytidine 
Synonyms
320-67-2 • 4-Amino-1-beta-d-ribofuranosyl-1,3,5-triazin-2(1H)-one • 4-Amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one • 5-AZAC • 5-azacitidine • 5-azacytidine • 5AzaC • Azacitidina • Azacitidina [INN-Spanish] • Azacitidine • Azacitidinum • Azacitidinum [INN-Latin] • C8H12N4O5 • Ladakamycin • Mylosar • NSC-102816 • NSC102816 • U-18496 • UNII-M801H13NRU • Vidaza 
CAS Number
320-67-2 
IUPAC Name
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one 
PubChem CID
9444 

Summary

Species No. Entries MAX(Avg/Med Lifespan Change %) MEAN(Avg/Med Lifespan Change %) MAX(Max Lifespan Change %) MEAN(Max Lifespan Change %)

Results

Compound/Formulation Species Sex Strain Dosage Avg/Med Lifespan Change (%) Avg/Med Lifespan Significance Max Lifespan Change (%) Reference

Lifespan Charts for Azacytidine


References

Tarkhov, AE et al. (2019) A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories. Sci Rep 9(1)7368 PubMed

DGIdb Human Drug-Gene Interactions for Azacytidine

Interaction Types Gene Symbol Common Name HGNC Id DGIdb Sources References

Stitch DB Human Drug-Protein Interactions for Azacytidine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id